| 题名 | Plant extracts and compounds for combating schistosomiasis |
| 作者 | |
| 发表日期 | 2023-12-01 |
| 发表期刊 | Phytochemistry Reviews |
| ISSN | 1568-7767 |
| 卷号 | 22 |
| 期号 | 6 |
| 页码 | 1691-1806 |
| 摘要 | Schistosomiasis is a vector-borne water-based disease caused by Schistosoma blood flukes. It mostly affects people in low-income regions, 90% of reported cases being in developing countries. Schistosoma has a complex lifecycle, alternately infecting mammalian hosts and snails. The snails hosting the parasite are the most viable targets. Selective preparations for reducing the parasite pool in snails and infected water are required as current molluscicides are also nontoxic to other organisms, including fish, and thus affect food supplies in infected areas. Plants (e.g. Annona crassiflora Mart., A. muricata L., and A. montana Macfad.) are attractive potential sources as alternative molluscicides and novel entity to treat the disease owned to their diverse biologically potent compounds including; saponins, alkaloids, terpenoids, and tannins. Additionally, they can be locally cultivated, providing income for farmers and reducing treatment costs. Here, we review plants, plant extracts and isolated compounds that have shown activities against the host snails or Schistosoma in various parts of its life cycle. Plants have a lot of potential and will continue to contribute feasible, effective medicines and/or pesticides; more research is warranted to fully explore their future applications. Graphical abstract: [Figure not available: see fulltext.]. |
| 关键词 | Glycoalkaloids Molluscicides Natural products Phorbol esters Saponins Schistosomiasis |
| DOI | 10.1007/s11101-022-09836-x |
| 相关网址 | 查看来源 |
| 语种 | 英语English |
| Scopus入藏号 | 2-s2.0-85140577094 |
| 引用统计 | |
| 文献类型 | 评论文章 |
| 条目标识符 | https://repository.uic.edu.cn/handle/39GCC9TT/11558 |
| 专题 | 北师香港浸会大学 |
| 通讯作者 | El-Seedi，Hesham R. |
| 作者单位 | 1.Pharmacognosy Group,Department of Pharmaceutical Biosciences,Biomedical Centre,Uppsala University,Uppsala,Box 591,751 24,Sweden 2.International Research Center for Food Nutrition and Safety,Jiangsu University,Zhenjiang,212013,China 3.International Joint Research Laboratory of Intelligent Agriculture and Agri-Products Processing (Jiangsu Education Department),Zhenjiang,212013,China 4.Department of Chemistry,Faculty of Science,Menoufia University,Shebin El-Kom,32512,Egypt 5.Department of Molecular Biosciences,The Wenner-Gren Institute,Stockholm University,Stockholm,106 91,Sweden 6.Division of Parasitology,Department of Zoology,Faculty of Science,Menoufia University,Shebin El-Kom,32512,Egypt 7.Chemistry Department of Medicinal and Aromatic Plants,Research Institute of Medicinal and Aromatic Plants (RIMAP),Beni-Suef University,Beni-Suef,62514,Egypt 8.School of Food and Biological Engineering,Jiangsu University,Zhenjiang,212013,China 9.College of Marine Sciences,Fujian Agriculture and Forestry University,Fuzhou,350002,China 10.Pests and Plant Protection Department,National Research Centre,Dokki, Cairo,Egypt 11.Dept. of Arid Land Agriculture,College of Agri. & Food Sciences,King Faisal University,Hofuf,P.O Box 55073,31982,Saudi Arabia 12.Gas Analysis and Fire Safety Laboratory,Chemistry Division,National Institute of Standards,Giza,136,12211,Egypt 13.Programme of Food Science and Technology,BNU-HKBU United International College,Zhuhai,China 14.Zoology Department,Faculty of Science,Menoufia University,Shebin El-Kom,32512,Egypt 15.Deartment of Physiology,School of Medicine,Mashhad,9177948564,Iran 16.Faculty of Medicine,Ain Shams University,Cairo,11591,Egypt 17.Department of Pharmaceutical Biology,Institute of Pharmaceutical and Biomedical Sciences,Johannes Gutenberg University,Mainz,Staudinger Weg 5,55128,Germany 18.Natural Products Laboratory,Institute of Biology,Leiden University,Leiden,Box 955,2300RA,Netherlands |
| 推荐引用方式 GB/T 7714 | El-Seedi，Hesham R.,Khalifa，Shaden A.M.,Mohamed，Azza H.et al. Plant extracts and compounds for combating schistosomiasis. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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