科研成果详情

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题名Natural Products from Herbal Medicine Self-Assemble into Advanced Bioactive Materials
作者
发表日期2024-09-18
发表期刊Advanced Science
ISSN2198-3844
卷号11
期号35
摘要

Novel biomaterials are becoming more crucial in treating human diseases. However, many materials require complex artificial modifications and synthesis, leading to potential difficulties in preparation, side effects, and clinical translation. Recently, significant progress has been achieved in terms of direct self-assembly of natural products from herbal medicine (NPHM), an important source for novel medications, resulting in a wide range of bioactive supramolecular materials including gels, and nanoparticles. The NPHM-based supramolecular bioactive materials are produced from renewable resources, are simple to prepare, and have demonstrated multi-functionality including slow-release, smart-responsive release, and especially possess powerful biological effects to treat various diseases. In this review, NPHM-based supramolecular bioactive materials have been revealed as an emerging, revolutionary, and promising strategy. The development, advantages, and limitations of NPHM, as well as the advantageous position of NPHM-based materials, are first reviewed. Subsequently, a systematic and comprehensive analysis of the self-assembly strategies specific to seven major classes of NPHM is highlighted. Insights into the influence of NPHM structural features on the formation of supramolecular materials are also provided. Finally, the drivers and preparations are summarized, emphasizing the biomedical applications, future scientific challenges, and opportunities, with the hope of igniting inspiration for future research and applications.

关键词bioactive materials natural products self-assembly strategy
DOI10.1002/advs.202403388
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收录类别SCIE
语种英语English
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science
WOS类目Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
WOS记录号WOS:001272909400001
Scopus入藏号2-s2.0-85198929615
引用统计
被引频次:36[WOS]   [WOS记录]     [WOS相关记录]
文献类型评论文章
条目标识符https://repository.uic.edu.cn/handle/39GCC9TT/11973
专题北师香港浸会大学
通讯作者Zheng, Jun
作者单位
1.School of Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China
2.Institute of Integrative Medicine, Department of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China
3.Center for Interdisciplinary Research in Traditional Chinese Medicine, Xiangya Hospital, Central South University, Changsha, 410008, China
4.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, China
5.College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China
6.Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, 519087, China
7.Hunan key laboratory of the research and development of novel pharmaceutical preparations, Changsha Medical University, Changsha, 410219, China
8.College of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, 410208, China
推荐引用方式
GB/T 7714
Guo, Xiaohang,Luo, Weikang,Wu, Lingyuet al. Natural Products from Herbal Medicine Self-Assemble into Advanced Bioactive Materials. 2024.
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