Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected with Flavobacterium columnare with an emphasis on immune responses

doi:10.1016/j.fsi.2014.12.006

科研成果详情

题名	Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected with Flavobacterium columnare with an emphasis on immune responses
作者	Zhou，Weidong 1; Zhang，Yulei 2,3; Wen，Yi 4; Ji，Wei 2,3; Zhou，Yang 3; Ji，Yachan 3; Liu，Xiaoling 3; Wang，Weimin 5; Asim，Muhammad 2,3; Liang，Xufang 2,5; Ai，Taoshan 1; Lin，Li 2,3,5
发表日期	2015
发表期刊	Fish and Shellfish Immunology
ISSN/eISSN	1050-4648
卷号	43 期号:1 页码:111-119
摘要	Flavobacterium columnare (FC) is the causative pathogen of columnaris which has caused great economic loss in fish culture worldwide, including in Mandarin fish (Siniperca chuatsi) culture. In the present study, the transcriptomic profiles of the head kidneys from FC-infected and non-infected Mandarin fish were obtained using HiSeq™ 2000 (Illumina). Totally 31,168 unigenes with high quality were obtained. Genes involved in protein folding, metabolism and energy, immune responses, oxidoreductase activity, cell growth and death were identified as enriched classes. 1019 differently expressed genes between the two groups were identified, including 603 up-regulated and 416 down-regulated genes. 27 differently expressed immune related genes were scrutinized, including 17 up-regulated and 10 down-regulated genes. Six of the differently expressed genes were further validated by qRT-PCR. The roles of the immune related genes were discussed. Identification of the host genes in response to FC infection will shed a new light on the prevention of columnaris.
关键词	Differently expressed genes Flavobacterium columnare Immune responses Siniperca chuatsi Transcriptome
DOI	10.1016/j.fsi.2014.12.006
URL	查看来源
语种	英语English
Scopus入藏号	2-s2.0-84942775711
引用统计	被引频次：43[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://repository.uic.edu.cn/handle/39GCC9TT/6467
专题	北师香港浸会大学
通讯作者	Liang，Xufang
作者单位	1.Wuhan Fishery Research Institute,Wuhan, Hubei,430207,China 2.Freshwater Aquaculture Collaborative Innovation Center of Hubei Province,Huazhong Agricultural University,Wuhan, Hubei,430070,China 3.Department of Aquatic Animal Medicine,College of Fisheries,Huazhong Agricultural University,Wuhan, Hubei,430070,China 4.Division of Science and Technology,Beijing Normal University,Hong Kong Baptist University United International College,Zhuhai, Guangdong,519085,China 5.China Key Lab of Freshwater Animal Breeding,Ministry of Agriculture,Wuhan, Hubei,430070,China
推荐引用方式 GB/T 7714	Zhou，Weidong,Zhang，Yulei,Wen，Yiet al. Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected with Flavobacterium columnare with an emphasis on immune responses[J]. Fish and Shellfish Immunology, 2015, 43(1): 111-119.
APA	Zhou，Weidong., Zhang，Yulei., Wen，Yi., Ji，Wei., Zhou，Yang., .. & Lin，Li. (2015). Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected with Flavobacterium columnare with an emphasis on immune responses. Fish and Shellfish Immunology, 43(1), 111-119.
MLA	Zhou，Weidong,et al."Analysis of the transcriptomic profilings of Mandarin fish (Siniperca chuatsi) infected with Flavobacterium columnare with an emphasis on immune responses". Fish and Shellfish Immunology 43.1(2015): 111-119.