| 发表状态 | 已发表Published |
| 题名 | A peptide nanofibrous indicator for eye-detectable cancer cell identification |
| 作者 | |
| 发表日期 | 2013-03-25 |
| 发表期刊 | Small
 |
| ISSN/eISSN | 1613-6810 |
| 卷号 | 9期号:6页码:920-926 |
| 摘要 | A unique peptide nanofibrous indicator (NFI) is fabricated by mixing a borono-peptide with alizarin red S, followed by subsequent binding and self-assembly. The NFI thus obtained exhibits an intense response to sialyl Lewis X tetrasaccharide, which is overexpressed in human hepatocellular carcinoma cell lines. Importantly, this NFI has the capability of specifically recognizing human hepatocellular liver carcinoma (HepG2) cells through the eye-detectable color change resulting from strong binding-induced displacement. This novel technique for cancer cell identification through direct unaided eye judgment will open up an innovative platform for cancer cell detection. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| 关键词 | cancer cells diagnostics nanofibers peptides self-assembly |
| DOI | 10.1002/smll.201201928 |
| URL | 查看来源 |
| 收录类别 | SCIE |
| 语种 | 英语English |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| WOS记录号 | WOS:000316338800016 |
| Scopus入藏号 | 2-s2.0-84875241628 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | https://repository.uic.edu.cn/handle/39GCC9TT/9109 |
| 专题 | 个人在本单位外知识产出 |
| 通讯作者 | Zhang, Xianzheng |
| 作者单位 | 1.Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry,Wuhan University,Wuhan 430072,China 2.Department of Fiber Science and Apparel Design,Cornell University,Ithaca, NY 14853,United States |
| 推荐引用方式 GB/T 7714 | Chen, Changsheng,Xu, Xiaoding,Wang, Yaet al. A peptide nanofibrous indicator for eye-detectable cancer cell identification[J]. Small, 2013, 9(6): 920-926. |
| APA | Chen, Changsheng., Xu, Xiaoding., Wang, Ya., Yang, Juan., Jia, Huizhen., .. & Zhang, Xianzheng. (2013). A peptide nanofibrous indicator for eye-detectable cancer cell identification. Small, 9(6), 920-926. |
| MLA | Chen, Changsheng,et al."A peptide nanofibrous indicator for eye-detectable cancer cell identification". Small 9.6(2013): 920-926. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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