| Title | A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides |
| Creator | |
| Date Issued | 2023-12-18 |
| Source Publication | Food and Function |
| ISSN | 2042-6496 |
| Volume | 15 |
| Issue | 2 |
| Pages | 481-492 |
| Abstract | Studies have shown that dietary polysaccharides, which are widely present in natural foods, have an important impact on the intestinal mucosal barrier. Dietary polysaccharides can maintain the intestinal barrier function through multiple mechanisms. The intestinal barrier is composed of mechanical, chemical, immune, and biological barriers, and dietary polysaccharides, as a bioactive component, can promote and regulate these four barriers. Dietary polysaccharides can enhance the expression of tight junction proteins and mucins such as occludin-1 and zonula occludens-1 (ZO-1) between intestinal epithelial cells, inhibit inflammatory response and oxidative stress, increase the growth of beneficial bacteria, produce beneficial metabolites such as short chain fatty acids (SCFAs), and promote the proliferation and metabolism of immune cells. Given the critical role of the intestinal mucosal system in health and disease, the protective effects of dietary polysaccharides may be potentially valuable for the prevention and treatment of gut-related diseases. Therefore, it is of great significance to further study the mechanism and application prospects of the intestinal mucosal barrier derived from plant, animal, fungal and bacterial sources. |
| DOI | 10.1039/d3fo03412g |
| URL | View source |
| Language | 英语English |
| Scopus ID | 2-s2.0-85182381737 |
| Citation statistics | |
| Document Type | Review |
| Identifier | http://repository.uic.edu.cn/handle/39GCC9TT/11553 |
| Collection | Beijing Normal-Hong Kong Baptist University |
| Corresponding Author | Xu，Baojun |
| Affiliation | 1.Food Science and Technology Program,Department of Life Sciences,BNU-HKBU United International College,China 2.Centre for Cancer and Inflammation Research,School of Chinese Medicine,Hong Kong Baptist University,Hong Kong,Hong Kong |
| First Author Affilication | Beijing Normal-Hong Kong Baptist University |
| Corresponding Author Affilication | Beijing Normal-Hong Kong Baptist University |
| Recommended Citation GB/T 7714 | Yan，Weiqi,Luo，Jinhai,Yu，Zhilinget al. A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides. 2023. |
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