A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides

doi:10.1039/d3fo03412g

科研成果详情

题名	A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides
作者	Yan，Weiqi 1,2; Luo，Jinhai 1,2; Yu，Zhiling 2; Xu，Baojun1
发表日期	2023-12-18
发表期刊	Food and Function
ISSN	2042-6496
卷号	15
期号	2
页码	481-492
摘要	Studies have shown that dietary polysaccharides, which are widely present in natural foods, have an important impact on the intestinal mucosal barrier. Dietary polysaccharides can maintain the intestinal barrier function through multiple mechanisms. The intestinal barrier is composed of mechanical, chemical, immune, and biological barriers, and dietary polysaccharides, as a bioactive component, can promote and regulate these four barriers. Dietary polysaccharides can enhance the expression of tight junction proteins and mucins such as occludin-1 and zonula occludens-1 (ZO-1) between intestinal epithelial cells, inhibit inflammatory response and oxidative stress, increase the growth of beneficial bacteria, produce beneficial metabolites such as short chain fatty acids (SCFAs), and promote the proliferation and metabolism of immune cells. Given the critical role of the intestinal mucosal system in health and disease, the protective effects of dietary polysaccharides may be potentially valuable for the prevention and treatment of gut-related diseases. Therefore, it is of great significance to further study the mechanism and application prospects of the intestinal mucosal barrier derived from plant, animal, fungal and bacterial sources.
DOI	10.1039/d3fo03412g
相关网址	查看来源
语种	英语English
Scopus入藏号	2-s2.0-85182381737
引用统计
文献类型	评论文章
条目标识符	https://repository.uic.edu.cn/handle/39GCC9TT/11553
专题	北师香港浸会大学
通讯作者	Xu，Baojun
作者单位	1.Food Science and Technology Program,Department of Life Sciences,BNU-HKBU United International College,China 2.Centre for Cancer and Inflammation Research,School of Chinese Medicine,Hong Kong Baptist University,Hong Kong,Hong Kong
第一作者单位	北师香港浸会大学
通讯作者单位	北师香港浸会大学
推荐引用方式 GB/T 7714	Yan，Weiqi,Luo，Jinhai,Yu，Zhilinget al. A critical review on intestinal mucosal barrier protection effects of dietary polysaccharides. 2023.