| Title | G protein-linked effector and second messenger systems involved in melatonin signal transduction |
| Creator | |
| Date Issued | 2003 |
| Source Publication | NeuroSignals |
| ISSN | 1424-862X |
| Volume | 12 |
| Issue | 2 |
| Pages | 59-70 |
| Abstract | The isolation and characterization of multiple melatonin receptors in a wide range of tissues and cells signifies the functional diversity of melatonin. In different cellular environments, melatonin can regulate distinct second messengers or even positively or negatively regulate the same signal transduction pathway. The capacity by which melatonin receptors modulate the activities of various effector molecules is determined by the complement of signaling components present in any particular cell type. The specific interactions between many signaling molecules have been discerned in an increasing number of cellular systems and this information is being used to explain the physiological actions of melatonin. This review will attempt to summarize recent research by many groups that has revealed numerous subtleties of the melatonin-coupled signaling pathways. Copyright © 2003 S. Karger AG, Basel. |
| Keyword | Adenylyl cyclase G proteins Ion channels Melatonin receptor Phospholipase C Signal transduction |
| DOI | 10.1159/000071815 |
| URL | View source |
| Language | 英语English |
| Scopus ID | 2-s2.0-0042387745 |
| Citation statistics | |
| Document Type | Review |
| Identifier | http://repository.uic.edu.cn/handle/39GCC9TT/11703 |
| Collection | Research outside affiliated institution |
| Corresponding Author | Wong，Yung H. |
| Affiliation | 1.Department of Biochemistry,Biotechnology Research Institute,Hong Kong University of Science and Technology,Hong Kong,Hong Kong 2.Department of Biochemistry,Biotechnology Research Institute,Hong Kong University of Science and Technology,Kowloon,Clear Water Bay,Hong Kong |
| Recommended Citation GB/T 7714 | New，David C.,Tsim，Siu T.,Wong，Yung H. G protein-linked effector and second messenger systems involved in melatonin signal transduction. 2003. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
BNBU 
Library
Edit Comment