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Status已发表Published
TitleGenomic prediction with NetGP based on gene network and multi-omics data in plants
Creator
Date Issued2025-04-01
Source PublicationPlant Biotechnology Journal
ISSN1467-7644
Volume23Issue:4Pages:1190-1201
Abstract

Genomic selection (GS) is a new breeding strategy. Generally, traditional methods are used for predicting traits based on the whole genome. However, the prediction accuracy of these models remains limited because they cannot fully reflect the intricate nonlinear interactions between genotypes and traits. Here, a novel single nucleotide polymorphism (SNP) feature extraction technique based on the Pearson-Collinearity Selection (PCS) is firstly presented and improves prediction accuracy across several known models. Furthermore, gene network prediction model (NetGP) is a novel deep learning approach designed for phenotypic prediction. It utilizes transcriptomic dataset (Trans), genomic dataset (SNP) and multi-omics dataset (Trans + SNP). The NetGP model demonstrated better performance compared to other models in genomic predictions, transcriptomic predictions and multi-omics predictions. NetGP multi-omics model performed better than independent genomic or transcriptomic prediction models. Prediction performance evaluations using several other plants' data showed good generalizability for NetGP. Taken together, our study not only offers a novel and effective tool for plant genomic selection but also points to new avenues for future plant breeding research.

Keyworddeep learning feature selection gene network genomic selection multi-omics predictions
DOI10.1111/pbi.14577
URLView source
Indexed BySCIE
Language英语English
WOS Research AreaBiotechnology & Applied Microbiology ; Plant Sciences
WOS SubjectBiotechnology & Applied Microbiology ; Plant Sciences
WOS IDWOS:001420584900001
Scopus ID2-s2.0-105001081982
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
Identifierhttp://repository.uic.edu.cn/handle/39GCC9TT/12807
CollectionBeijing Normal-Hong Kong Baptist University
Corresponding AuthorXu, Zhi
Affiliation
1.Guilin University of Electronic Technology,Guilin,China
2.Rice Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou,China
3.Key Laboratory of Genetics and Breeding of High Quality Rice in Southern China (Co-construction by Ministry and Province),Ministry of Agriculture and Rural Affairs,Guangzhou,China
4.Guangdong Key Laboratory of New Technology in Rice Breeding,Guangzhou,China
5.Guangdong Rice Engineering Laboratory,Guangzhou,China
6.Guangdong Provincial Key Laboratory of Crop Genetic Improvement,Crops Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou,China
7.Beijing Normal University - Hong Kong Baptist University United International College,Zhuhai,China
8.Guangdong Provincial Key Laboratory of Biotechnology for Plant Development,School of Life Sciences,South China Normal University,Guangzhou,Guangdong,China
Recommended Citation
GB/T 7714
Zhao, Longyang,Tang, Ping,Luo, Jinjinget al. Genomic prediction with NetGP based on gene network and multi-omics data in plants[J]. Plant Biotechnology Journal, 2025, 23(4): 1190-1201.
APA Zhao, Longyang., Tang, Ping., Luo, Jinjing., Liu, Jianxiang., Peng, Xin., .. & Liu, Qi. (2025). Genomic prediction with NetGP based on gene network and multi-omics data in plants. Plant Biotechnology Journal, 23(4), 1190-1201.
MLA Zhao, Longyang,et al."Genomic prediction with NetGP based on gene network and multi-omics data in plants". Plant Biotechnology Journal 23.4(2025): 1190-1201.
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