Status | 已发表Published |
Title | Electric potential generation of electrocytes: Modelling, analysis, and computation |
Creator | |
Date Issued | 2020 |
Source Publication | Journal of Theoretical Biology
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ISSN | 0022-5193 |
Volume | 487 |
Abstract | In this paper, we developed a one-dimensional model for electric potential generation of electrocytes in electric eels. The model is based on the Poisson–Nernst–Planck system for ion transport coupled with membrane fluxes including the Hodgkin–Huxley type. Using asymptotic analysis, we derived a simplified zero-dimensional model, which we denote as the membrane model in this paper, as a leading order approximation. Our analysis provides justification for the assumption in membrane models that electric potential is constant in the intracellular space. This is essential to explain the superposition of two membrane potentials that leads to a significant transcellular potential. Numerical simulations are also carried out to support our analytical findings. © 2019 Elsevier Ltd |
Keyword | Asymptotic analysis Electrocyte Numerical simulation Poisson–Nernst–Planck system Voltage generation |
DOI | 10.1016/j.jtbi.2019.110107 |
URL | View source |
Indexed By | SCIE |
Language | 英语English |
WOS Research Area | ife Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology |
WOS Subject | Biology ; Mathematical & Computational Biology |
WOS ID | WOS:000509005400012 |
Citation statistics | |
Document Type | Journal article |
Identifier | http://repository.uic.edu.cn/handle/39GCC9TT/2161 |
Collection | Faculty of Science and Technology |
Corresponding Author | Huang, Huaxiong |
Affiliation | 1.Department of Mathematics and Statistics, York University, Toronto, Canada 2.Department of Applied Mathematics, Feng Chia University, Taichung, 40724, Taiwan 3.National Center for Theoretical Sciences, Taipei Office, Taipei, 10617, Taiwan 4.BNU-UIC Joint Mathematical Research Centre, Zhuhai, China, China 5.Department of Computer Science, University of Toronto, Toronto, Canada |
Recommended Citation GB/T 7714 | Cao, Xiulei,Song, Zilong,Horng, Tzyy-Lenget al. Electric potential generation of electrocytes: Modelling, analysis, and computation[J]. Journal of Theoretical Biology, 2020, 487. |
APA | Cao, Xiulei, Song, Zilong, Horng, Tzyy-Leng, & Huang, Huaxiong. (2020). Electric potential generation of electrocytes: Modelling, analysis, and computation. Journal of Theoretical Biology, 487. |
MLA | Cao, Xiulei,et al."Electric potential generation of electrocytes: Modelling, analysis, and computation". Journal of Theoretical Biology 487(2020). |
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