| Title | Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish |
| Creator | |
| Date Issued | 2015-04-01 |
| Source Publication | Journal of General Virology
 |
| ISSN | 0022-1317 |
| Volume | 96Issue:4Pages:775-781 |
| Abstract | Members of the genus Vesiculovirus, which belongs to the family Rhabdoviridae, can cause great economic loss in fish culture. In the present report, a vesiculovirus [named snakehead fish vesiculovirus (SHVV)] was isolated from diseased hybrid snakehead fish. SHVV shared 94% nucleotide sequence identity at the genomic level with Siniperca chuatsi rhabdovirus (SCRV), which infects mandarin fish (S. chuatsi). We showed that SHVV was able to replicate and proliferate well in SSN-1 cells, which originate from striped snakehead fish (Channa striatus). Furthermore, mandarin fish was susceptible to SHVV by bath exposure, as well as by intraperitoneal injection. The infected fish showed typical clinical signs of rhabdovirus infection, including haemorrhage and oedema. Histopathological analysis revealed that extensive inflammation and necrosis were observed in the spleen, kidney, liver, heart and brain of the moribund mandarin fish. These results will shed new light on the epidemic of vesiculovirus infections among fish. |
| DOI | 10.1099/vir.0.000037 |
| URL | View source |
| Language | 英语English |
| Scopus ID | 2-s2.0-84924991206 |
| Citation statistics | |
| Document Type | Journal article |
| Identifier | http://repository.uic.edu.cn/handle/39GCC9TT/6474 |
| Collection | Beijing Normal-Hong Kong Baptist University |
| Corresponding Author | Lin，Li |
| Affiliation | 1.Department of Aquatic Animal Medicine,College of Fisheries,Huazhong Agricultural University,Wuhan,430070,China 2.Freshwater Aquaculture Collaborative Innovation Center of Hubei Province,Wuhan,430070,China 3.Division of Science and Technology,Beijing Normal University,Hong Kong Baptist University United International College,Zhuhai,519085,China 4.School of Biological Sciences,Lake Superior State University,Sault Ste. Marie,49783,United States 5.Institute of Marine and Environmental Technology,University of Maryland,Baltimore,21202,United States 6.Key Lab of Freshwater Animal Breeding,Ministry of Agriculture,Wuhan,430070,China |
| Recommended Citation GB/T 7714 | Liu，Xiaodan,Wen，Yi,Hu，Xianqinet al. Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish[J]. Journal of General Virology, 2015, 96(4): 775-781. |
| APA | Liu，Xiaodan., Wen，Yi., Hu，Xianqin., Wang，Wenwen., Liang，Xufang., .. & Lin，Li. (2015). Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish. Journal of General Virology, 96(4), 775-781. |
| MLA | Liu，Xiaodan,et al."Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish". Journal of General Virology 96.4(2015): 775-781. |
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