发表状态 | 已发表Published |
题名 | New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity |
作者 | |
发表日期 | 2020-07-15 |
发表期刊 | Food Chemistry
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ISSN/eISSN | 0308-8146 |
卷号 | 318 |
摘要 | Excessive energy intake, poor physical exercise and genetics/epigenetics are instrumental for the development of obesity. Because of rapidly emerging evidences related to off-target effects and toxicity of anti-obesity drugs, there is a need to search for more effective and targeted drugs for treatment of obesity. Substantial studies have found the nutritional effects of dietary saponins (bio-detergents) in terms of decreasing the synthesis of lipids, suppressing adipogenesis, inhibiting intestinal absorption of lipids, and promoting fecal excretion of bile acids and triglycerides. Dietary saponin have been approved as potent pancreatic lipase inhibitors, disaccharidase enzyme inhibitors, antagonistic to in vitro lipogenesis and in vivo appetite suppressants, antioxidants, immune-regulators, prevent fatty liver formation, protects epithelial vasculature and regulate body weight. Many dietary saponins, such as sibutramine, morgoside, sessiloside, soysaponin B, and diosgenin, have treatment potential against the development of obesity. Excellent scientific achievements have been developed for a better understanding the mechanism of saponins in preventing obesity. |
关键词 | Anti-obesity Dietary saponins Whole grain Pancreatic lipase SREBP-1 |
DOI | 10.1016/j.foodchem.2020.126474 |
URL | 查看来源 |
收录类别 | SCIE ; CPCI-S |
语种 | 英语English |
WOS研究方向 | Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics |
WOS类目 | Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics |
WOS记录号 | WOS:000520858000041 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://repository.uic.edu.cn/handle/39GCC9TT/1054 |
专题 | 理工科技学院 |
通讯作者 | Xu, Baojun |
作者单位 | 1.Food Science and Technology Program,Beijing Normal University-Hong Kong Baptist University United International College,Zhuhai,519087,China 2.Hebei Normal University of Science and Technology,Qinhuangdao,066600,China 3.Kazakhstan Medical University “KSPH”,Almaty,050060,Kazakhstan |
第一作者单位 | 北师香港浸会大学 |
通讯作者单位 | 北师香港浸会大学 |
推荐引用方式 GB/T 7714 | Jeepipalli, Syam P.K.,Du, Bin,Sabitaliyevich, Uteuliyev Y.et al. New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity[J]. Food Chemistry, 2020, 318. |
APA | Jeepipalli, Syam P.K., Du, Bin, Sabitaliyevich, Uteuliyev Y., & Xu, Baojun. (2020). New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity. Food Chemistry, 318. |
MLA | Jeepipalli, Syam P.K.,et al."New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity". Food Chemistry 318(2020). |
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