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题名New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity
作者
发表日期2020-07-15
发表期刊Food Chemistry
ISSN/eISSN0308-8146
卷号318
摘要

Excessive energy intake, poor physical exercise and genetics/epigenetics are instrumental for the development of obesity. Because of rapidly emerging evidences related to off-target effects and toxicity of anti-obesity drugs, there is a need to search for more effective and targeted drugs for treatment of obesity. Substantial studies have found the nutritional effects of dietary saponins (bio-detergents) in terms of decreasing the synthesis of lipids, suppressing adipogenesis, inhibiting intestinal absorption of lipids, and promoting fecal excretion of bile acids and triglycerides. Dietary saponin have been approved as potent pancreatic lipase inhibitors, disaccharidase enzyme inhibitors, antagonistic to in vitro lipogenesis and in vivo appetite suppressants, antioxidants, immune-regulators, prevent fatty liver formation, protects epithelial vasculature and regulate body weight. Many dietary saponins, such as sibutramine, morgoside, sessiloside, soysaponin B, and diosgenin, have treatment potential against the development of obesity. Excellent scientific achievements have been developed for a better understanding the mechanism of saponins in preventing obesity.

关键词Anti-obesity Dietary saponins Whole grain Pancreatic lipase SREBP-1
DOI10.1016/j.foodchem.2020.126474
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收录类别SCIE ; CPCI-S
语种英语English
WOS研究方向Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS类目Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
WOS记录号WOS:000520858000041
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被引频次:46[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符https://repository.uic.edu.cn/handle/39GCC9TT/1054
专题理工科技学院
通讯作者Xu, Baojun
作者单位
1.Food Science and Technology Program,Beijing Normal University-Hong Kong Baptist University United International College,Zhuhai,519087,China
2.Hebei Normal University of Science and Technology,Qinhuangdao,066600,China
3.Kazakhstan Medical University “KSPH”,Almaty,050060,Kazakhstan
第一作者单位北师香港浸会大学
通讯作者单位北师香港浸会大学
推荐引用方式
GB/T 7714
Jeepipalli, Syam P.K.,Du, Bin,Sabitaliyevich, Uteuliyev Y.et al. New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity[J]. Food Chemistry, 2020, 318.
APA Jeepipalli, Syam P.K., Du, Bin, Sabitaliyevich, Uteuliyev Y., & Xu, Baojun. (2020). New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity. Food Chemistry, 318.
MLA Jeepipalli, Syam P.K.,et al."New insights into potential nutritional effects of dietary saponins in protecting against the development of obesity". Food Chemistry 318(2020).
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