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题名Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives
作者
发表日期2021-04-01
发表期刊Cancer Letters
ISSN/eISSN0304-3835
卷号502页码:97-107
摘要

Nearly 70% of ovarian cancer (OC) patients experience recurrence within the first 2 years after initial treatment. Emerging evidence indicates that long non-coding RNAs (lncRNAs) play a pivotal role in the pathogenesis of OC progression, resistance to therapy and recurrent OC (ROC). Transcriptome profiling studies have reported differential expression patterns of lncRNAs in OC which are related to increased cell invasion, metastasis and drug resistance. In this review, we highlighted the roles of lncRNAs in OC progression and outlined the potential molecular mechanisms by which lncRNAs impact on ROC. Recent advances using lncRNAs as potential biomarkers for screening, detection, prediction, response to therapy and as therapeutic targets are discussed.

关键词Cancer biomarker Drug resistance LncRNA Metastasis Recurrence ROC
DOI10.1016/j.canlet.2020.12.042
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收录类别SCIE
语种英语English
WOS研究方向Oncology
WOS类目Oncology
WOS记录号WOS:000619210000009
Scopus入藏号2-s2.0-85099393997
引用统计
被引频次:22[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符https://repository.uic.edu.cn/handle/39GCC9TT/13167
专题个人在本单位外知识产出
通讯作者Pandey, Vijay
作者单位
1.Tsinghua Berkeley Shenzhen Institute,Tsinghua Shenzhen International Graduate School,Tsinghua University,Shenzhen,518055,China
2.Institute of Biopharmaceutical and Health Engineering,Tsinghua Shenzhen International Graduate School,Tsinghua University,Shenzhen,518055,China
3.Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences,University of Science and Technology of China,Hefei,230000,China
4.The CAS Key Laboratory of Innate Immunity and Chronic Disease,School of Life Sciences,University of Science and Technology of China,Hefei,230000,China
5.Shenzhen Bay Laboratory,Shenzhen,518055,China
推荐引用方式
GB/T 7714
Bhardwaj, Vipul,Tan, Yan Qin,Wu, Ming Minget al. Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives[J]. Cancer Letters, 2021, 502: 97-107.
APA Bhardwaj, Vipul., Tan, Yan Qin., Wu, Ming Ming., Ma, Lan., Zhu, Tao., .. & Pandey, Vijay. (2021). Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives. Cancer Letters, 502, 97-107.
MLA Bhardwaj, Vipul,et al."Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives". Cancer Letters 502(2021): 97-107.
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