发表状态 | 已发表Published |
题名 | Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives |
作者 | |
发表日期 | 2021-04-01 |
发表期刊 | Cancer Letters
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ISSN/eISSN | 0304-3835 |
卷号 | 502页码:97-107 |
摘要 | Nearly 70% of ovarian cancer (OC) patients experience recurrence within the first 2 years after initial treatment. Emerging evidence indicates that long non-coding RNAs (lncRNAs) play a pivotal role in the pathogenesis of OC progression, resistance to therapy and recurrent OC (ROC). Transcriptome profiling studies have reported differential expression patterns of lncRNAs in OC which are related to increased cell invasion, metastasis and drug resistance. In this review, we highlighted the roles of lncRNAs in OC progression and outlined the potential molecular mechanisms by which lncRNAs impact on ROC. Recent advances using lncRNAs as potential biomarkers for screening, detection, prediction, response to therapy and as therapeutic targets are discussed. |
关键词 | Cancer biomarker Drug resistance LncRNA Metastasis Recurrence ROC |
DOI | 10.1016/j.canlet.2020.12.042 |
URL | 查看来源 |
收录类别 | SCIE |
语种 | 英语English |
WOS研究方向 | Oncology |
WOS类目 | Oncology |
WOS记录号 | WOS:000619210000009 |
Scopus入藏号 | 2-s2.0-85099393997 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://repository.uic.edu.cn/handle/39GCC9TT/13167 |
专题 | 个人在本单位外知识产出 |
通讯作者 | Pandey, Vijay |
作者单位 | 1.Tsinghua Berkeley Shenzhen Institute,Tsinghua Shenzhen International Graduate School,Tsinghua University,Shenzhen,518055,China 2.Institute of Biopharmaceutical and Health Engineering,Tsinghua Shenzhen International Graduate School,Tsinghua University,Shenzhen,518055,China 3.Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences,University of Science and Technology of China,Hefei,230000,China 4.The CAS Key Laboratory of Innate Immunity and Chronic Disease,School of Life Sciences,University of Science and Technology of China,Hefei,230000,China 5.Shenzhen Bay Laboratory,Shenzhen,518055,China |
推荐引用方式 GB/T 7714 | Bhardwaj, Vipul,Tan, Yan Qin,Wu, Ming Minget al. Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives[J]. Cancer Letters, 2021, 502: 97-107. |
APA | Bhardwaj, Vipul., Tan, Yan Qin., Wu, Ming Ming., Ma, Lan., Zhu, Tao., .. & Pandey, Vijay. (2021). Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives. Cancer Letters, 502, 97-107. |
MLA | Bhardwaj, Vipul,et al."Long non-coding RNAs in recurrent ovarian cancer: Theranostic perspectives". Cancer Letters 502(2021): 97-107. |
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