Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish

doi:10.1099/vir.0.000037

科研成果详情

题名	Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish
作者	Liu，Xiaodan 1,2; Wen，Yi 3; Hu，Xianqin 1,2; Wang，Wenwen 1,2; Liang，Xufang 2; Li，Jun 4; Vakharia，Vikram 5; Lin，Li 1,2,6
发表日期	2015-04-01
发表期刊	Journal of General Virology
ISSN/eISSN	0022-1317
卷号	96 期号:4 页码:775-781
摘要	Members of the genus Vesiculovirus, which belongs to the family Rhabdoviridae, can cause great economic loss in fish culture. In the present report, a vesiculovirus [named snakehead fish vesiculovirus (SHVV)] was isolated from diseased hybrid snakehead fish. SHVV shared 94% nucleotide sequence identity at the genomic level with Siniperca chuatsi rhabdovirus (SCRV), which infects mandarin fish (S. chuatsi). We showed that SHVV was able to replicate and proliferate well in SSN-1 cells, which originate from striped snakehead fish (Channa striatus). Furthermore, mandarin fish was susceptible to SHVV by bath exposure, as well as by intraperitoneal injection. The infected fish showed typical clinical signs of rhabdovirus infection, including haemorrhage and oedema. Histopathological analysis revealed that extensive inflammation and necrosis were observed in the spleen, kidney, liver, heart and brain of the moribund mandarin fish. These results will shed new light on the epidemic of vesiculovirus infections among fish.
DOI	10.1099/vir.0.000037
URL	查看来源
语种	英语English
Scopus入藏号	2-s2.0-84924991206
引用统计	被引频次：47[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://repository.uic.edu.cn/handle/39GCC9TT/6474
专题	北师香港浸会大学
通讯作者	Lin，Li
作者单位	1.Department of Aquatic Animal Medicine,College of Fisheries,Huazhong Agricultural University,Wuhan,430070,China 2.Freshwater Aquaculture Collaborative Innovation Center of Hubei Province,Wuhan,430070,China 3.Division of Science and Technology,Beijing Normal University,Hong Kong Baptist University United International College,Zhuhai,519085,China 4.School of Biological Sciences,Lake Superior State University,Sault Ste. Marie,49783,United States 5.Institute of Marine and Environmental Technology,University of Maryland,Baltimore,21202,United States 6.Key Lab of Freshwater Animal Breeding,Ministry of Agriculture,Wuhan,430070,China
推荐引用方式 GB/T 7714	Liu，Xiaodan,Wen，Yi,Hu，Xianqinet al. Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish[J]. Journal of General Virology, 2015, 96(4): 775-781.
APA	Liu，Xiaodan., Wen，Yi., Hu，Xianqin., Wang，Wenwen., Liang，Xufang., .. & Lin，Li. (2015). Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish. Journal of General Virology, 96(4), 775-781.
MLA	Liu，Xiaodan,et al."Breaking the host range: Mandarin fish is susceptible to a vesiculovirus derived from snakehead fish". Journal of General Virology 96.4(2015): 775-781.