Status | 已发表Published |
Title | Regulation of cell signaling pathways by berberine in different cancers: Searching for missing pieces of an incomplete JIG-saw puzzle for an effective cancer therapy |
Creator | |
Date Issued | 2019-04-01 |
Source Publication | Cancers
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ISSN | 2072-6694 |
Volume | 11Issue:4 |
Abstract | There has been a renewed interest in the identification of natural products having premium pharmacological properties and minimum off-target effects. In accordance with this approach, natural product research has experienced an exponential growth in the past two decades and has yielded a stream of preclinical and clinical insights which have deeply improved our knowledge related to the multifaceted nature of cancer and strategies to therapeutically target deregulated signaling pathways in different cancers. In this review, we have set the spotlight on the scientifically proven ability of berberine to effectively target a myriad of deregulated pathways. |
Keyword | Berberine Cancer Therapy MicroRNAs Oncogenic cascades Signaling pathways TRAIL |
DOI | 10.3390/cancers11040478 |
URL | View source |
Language | 英语English |
WOS Research Area | Oncology |
WOS Subject | Oncology |
WOS ID | WOS:000467773400046 |
Citation statistics | |
Document Type | Journal article |
Identifier | http://repository.uic.edu.cn/handle/39GCC9TT/1203 |
Collection | Faculty of Science and Technology |
Corresponding Author | Xu, Baojun |
Affiliation | 1.Department of Molecular Oncology,Institute of Biomedical and Genetic Engineering (IBGE),Islamabad,44000,Pakistan 2.Department of Chemistry,GCU,Lahore,54000,Pakistan 3.Department of Bioinformatics and Biotechnology,International Islamic University,Islamabad,44000,Pakistan 4.Department of Obstetrics and Gynecology,Yeditepe University Hospital,Istanbul,34755,Turkey 5.Istituto Italiano di Tecnologia,Smart Bio-Interfaces,Pisa,Pontedera,56025,Italy 6.Department of Postgraduate Education and Research,Kazakhstan Medical University KSPH,Almaty,050004,Kazakhstan 7.Department of General Surgery,Kazakhstan Medical University KSPH,Almaty,050004,Kazakhstan 8.Department of Biomedical Science,Institute of Biomedicine and Molecular Immunology “A. Monroy”,National Research Council,Palermo,90146,Italy 9.Department of Agrifood,National Research Council Italy Institute of Sciences of Food Productions (CNR-ISPA),Lecce,Via Lecce-Monteroni km 7,73100,Italy 10.Division of Science and Technology,Beijing Normal University-Hong Kong Baptist University United International College,Zhuhai,519087,China |
Corresponding Author Affilication | Beijing Normal-Hong Kong Baptist University |
Recommended Citation GB/T 7714 | Farooqi, Ammad Ahmad,Qureshi, Muhammad Zahid,Khalid, Sumbulet al. Regulation of cell signaling pathways by berberine in different cancers: Searching for missing pieces of an incomplete JIG-saw puzzle for an effective cancer therapy[J]. Cancers, 2019, 11(4). |
APA | Farooqi, Ammad Ahmad., Qureshi, Muhammad Zahid., Khalid, Sumbul., Attar, Rukset., Martinelli, Chiara., .. & Xu, Baojun. (2019). Regulation of cell signaling pathways by berberine in different cancers: Searching for missing pieces of an incomplete JIG-saw puzzle for an effective cancer therapy. Cancers, 11(4). |
MLA | Farooqi, Ammad Ahmad,et al."Regulation of cell signaling pathways by berberine in different cancers: Searching for missing pieces of an incomplete JIG-saw puzzle for an effective cancer therapy". Cancers 11.4(2019). |
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Farooqi-2019-Regulat(2127KB) | Journal article | Published draft | Open Access | CC BY-NC-SA | View Download |
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